Irf7 mouse

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August undefined, 2024

WebApr 7, 2005 · Consistently, Irf7-/- mice are more vulnerable than Myd88-/- mice to viral infection, and this correlates with a marked decrease in serum IFN levels, indicating the … WebImmunohistochemistry-Paraffin: IRF7 Antibody (SC0617) [NBP2-67634] - Analysis of paraffin-embedded mouse liver tissue using anti-IRF7 antibody. Counter stained with hematoxylin. Flow Cytometry: IRF7 Antibody (SC0617) [NBP2-67634] - Analysis of Jurkat cells with IRF7 antibody at 1/50 dilution (red) compared with an unlabelled control (cells ...

IRF7 Antibody - BSA Free (NBP1-77263): Novus …

WebJul 7, 2024 · It remains possible that IRF7, a homolog of IRF3, compensates for the loss of IRF3 and explains the IRF3-independent resistance to HSV-1 that we observe. ... Mouse primary microglia cells and ... http://www.informatics.jax.org/allele/allgenoviews/MGI:3577089 green bay packer power recliner

Interferon regulatory factor 3 is a key regulation factor for inducing …

WebUse of MICE by companies or for-profit entities requires a license prior to shipping. Licensing Information Phone: 207-288-6470 Email: [email protected] Payment Terms and Conditions Terms are granted by individual review and stated … WebJul 14, 2016 · IRF3-5D, an active form of IRF3, and IRF7Δ247–467, a constitutively active form of IRF7 were constructed as previously described using pFLAG-IRF3, and pFLAG-IRF7 plasmids as templates 38,39,40 ... WebIrf7 Name interferon regulatory factor 7 Feature Type protein coding gene IDs MGI:1859212 NCBI Gene: 54123 Alliance gene page Transcription Start Sites 17 TSS Location & Maps … flower shop mount horeb wi

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WebRestoration of IRF7 in tumor cells isolated from metastatic mouse primary mammary tumors restored the ability to secrete IFN and reduced the metastatic burden in a breast cancer tumor mouse model [165]. Decreased IRF7 expression levels were found to correlate with increased metastatic events in human breast cancer, supporting the notion that ... WebImmunohistochemistry (Paraffin) analysis of IRF7 in paraffin-embedded mouse heart tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes.The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with IRF7 Recombinant ... green bay packer player arrestedWebMay 21, 2024 · By combining DNA microarray and genomic data analyses to predict DNA binding motifs, we identified the transcription factor Interferon Regulatory Factor 7 (IRF7) as a possible regulator of genes related to adipocyte hypertrophy. green bay packer polo shirts for men

"WebInterferon regulatory receptor 7 (IRF7) is a transcription factor involved in the activation of the type I interferon (IFN) response upon pathogenic infection [3-4]. IRF7 has been implicated downstream of several pattern recognition receptors (PRRs), including TLRs, RLRs, and DNA sensors [2]. " - Irf7 mouse

Irf7 mouse

Purified anti-IRF7 Antibody anti-IRF7 - W16064A - BioLegend

WebIRF7 Antibody (PA5-20281) in IHC Immunohistochemistry of IRF7 in mouse spleen tissue with IRF7 Polyclonal Antibody (Product # PA5-20281) at 5 µg/mL. Product Details Product Specific Information A suggested positive control is 293 cell lysate. PA5-20281 can be used with blocking peptide PEP-0415. Target Information WebApr 13, 2024 · RNA sequencing analysis of IRF7 CRISPRa and CRISPRi- DF-1 cells revealed the specificity of CRISPRa and CRISPRi-based targeted transcriptional regulation with minimal off-target effects. ... Cox, T.; Melvin, D.; Wang, X.; Bradley, A.; Liu, P. Chromosomal transposition of PiggyBac in mouse embryonic stem cells. Proc. Natl. Acad. Sci. USA …

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WebJun 19, 2024 · To elucidate pDC immunomodulatory functions, we developed a mouse model in which IRF7 signaling is restricted to pDC. Despite undetectable levels of IFN-I protein, pDC-restricted IRF7 signaling controlled both viruses and was sufficient to protect mice from lethal CHIKV infection. Early pDC IRF7-signaling resulted in amplification of … WebPE Mouse anti-IRF-7 This SKU will be discontinuing June 2024. For additional support, contact your local applications specialist. Contact Us PE Mouse anti-IRF-7 Clone K40-321 …

WebIRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at … WebJan 18, 2024 · It has been proposed, based on studies of mouse Ifna4 and Ifna2 genes , that late-phase expression of IFNA genes is controlled by Irf7 binding to VRE-A/B, whereas early-phase expression is controlled by Irf3 binding to VRE-C. We show that for many IFNs (63%, 17/27) it is only IRF7 that binds to VRE-A/B, suggesting that late-phase expression ...

WebPrimePCR™ PreAmp for SYBR® Green Assay: Irf7, Mouse Reaction: 400 reactions Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis. WebPrimePCR™ Template for SYBR® Green Assay: Irf7, Mouse Reaction: 200 x 20 µl reactions desalted Gene-specific synthetic DNA template designed to give a positive real-time PCR …

WebJan 10, 2024 · IRF7 is the key transcription factor which induces IFNα expression 9, leading to a second wave of type I IFN release. Since IFNα signals via the IFNAR this leads to a positive feedback loop that...

WebNov 30, 2024 · IRF7 could regulate the transcription of Usp25 in mouse embryonic fibroblast (MEFs) and BM-derived dendritic cells (BMDCs) in response to viral infection or LPS. 42 It was reported that Usp25 binds with the promoter of Sox2 that played an important role in the pluripotency of embryonic stem cells development. 43, 44 Whether Usp25 is a potential ... flower shop mount pleasant txWebPhospho-IRF-7 (Ser437/438) (D6M2I) Rabbit mAb (Mouse Specific) recognizes endogenous levels of mouse IRF-7 protein when dually phosphorylated at Ser437 and Ser438. This … green bay packer press conferenceWebOct 18, 2024 · Interferon regulatory factor 7 (IRF7) is the main transcriptional regulator of type I IFN, and it is crucial for the induction of IFNα/β and the type I IFN-dependent immune response. In this... flower shop mount pearl nlWebPE Mouse anti-IRF-7 This SKU will be discontinuing June 2024. For additional support, contact your local applications specialist. Contact Us PE Mouse anti-IRF-7 Clone K40-321 (RUO) View all Formats Analysis of IRF-7 in transfected human epithelial cells. green bay packer practice scheduleWebApr 14, 2011 · IRF7 is a lymphoid-specific factor, which is constitutively expressed in the cytoplasm in B cells, pDCs and monocytes in the spleen, thymus, and peripheral blood … green bay packer poncho sweaterWebProduct Details. Partial mouse IRF7 recombinant protein (127-487a.a.) expressed in E. coli. Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. The antibody was purified by affinity chromatography. The antibody solution should be stored undiluted between 2°C and 8°C. green bay packer picks up ballWebUsing the International Mouse Strain Resource Mouse lines carrying: Irf7 tm1Ttg mutation (2 available); any Irf7 mutation (16 available) ♀ phenotype observed in females green bay packer practice schedule 2022