WebMar 19, 2024 · Cancer is a common malignant disease worldwide with an increasing mortality in recent years. Salvia miltiorrhiza, a well-known traditional Chinese medicine, has been used for the treatment of cardiovascular and cerebrovascular diseases for thousands of years. The liposoluble tanshinones in S. miltiorrhiza are important bioactive … WebJan 1, 2009 · Cryptotanshinone was colocalized with STAT3 molecules in the cytoplasm and inhibited the formation of STAT3 dimers. Computational modeling showed that cryptotanshinone could bind to the SH2 domain of STAT3. These results suggest that cryptotanshinone is a potent anticancer agent targeting the activation STAT3 protein. It is …

Cryptotanshinone ≥99%(HPLC) Selleck STAT inhibitor

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Abstract 5269: Cryptotanshinone activate Nrf2 expression through …

WebCryptotanshinone (CPT), isolated from the plant Salvia miltiorrhiza Bunge, is a potential anticancer agent. However, the underlying mechanism remains to be defined. Here, we show that CPT inhibited lymphangiogenesis in an in vitro model (tube formation). ... 隐丹参酮, ≥98% (HPLC) Pricing ... WebJan 2, 2011 · 4种丹参酮类化合物均对spc-a-1细胞具有明显的增殖抑制作用，作用强度大小依次为二氢丹参酮Ⅰ、丹参酮Ⅰ、丹参酮Ⅱa、隐丹参酮，提示a环为芳环时可增强细胞毒性，c … WebCryptotanshinone is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. Cryptotanshinone … greek name for theodore